SiaFind™ Pan-Specific Lectenz® is a sialic acid affinity reagent for the detection, separation and enrichment of sialoglycans terminating in Siaα2,3Gal, Siaα2,6Gal, and Siaα2,8Sia commonly found in glycoconjugates (glycoproteins, glycolipids, and oligo- or polysaccharides). It has high affinity and specificity towards sialoglycans in a linkage independent manner (pan-specific). This reagent can be employed as a capture reagent in a variety of applications.
SiaRich™ Pan-Specific Resin (Cat #SR0501) is an agarose resin coupled with a recombinant tandem repeat of the SiaFind™ Pan-Specific Lectenz® and is designed for the rapid and specific enrichment of sialoglycoconjugates terminating in Siaα2,3Gal, Siaα2,6Gal, and Siaα2,8Sia from a complex sample. Specifically bound sialylated glycoconjugates are non-competitively eluted from the resin for downstream analysis such as mass spectrometry, ELISA, and Western blotting.
Supplementary Information
Form and Storage
The SiaRich™ Pan-Specific Resin is supplied as a 50% slurry in Tris Buffered Saline ready for affinity chromatography. The kit includes 2 bottles of 5X Binding Buffer 5 (Cat #BA0105) for equilibration, binding, washing, and storage.
