SiaFind™ α2,3-Specific Lectenz® is a sialic acid affinity reagent for the detection, separation and enrichment of
sialoglycans terminating in Neu5Acα2,3Gal commonly found in glycoconjugates (glycoproteins, glycolipids, and oligo- or
polysaccharides). It has high affinity and specificity towards α2,3 linked sialic acids on glycans. However, it does not bind
effectively to branched sialylated epitopes such as sialyl Lewis A/X. This reagent can be employed as a capture reagent in
a variety of applications.
The SiaRich™ α2,3-Specific Column (Cat #SC2301) is a SiaFind™ α2,3-Specific Lectenz®-coupled column for rapid enrichment and purification of α2,3-linked sialoglycoconjugates by affinity chromatography. Specifically bound sialylated glycoproteins or other biomolecules may be eluted competitively or non-competitively from the column.