Glyco Enzymes


Carbohydrates play a vast role in biology, from cell recognition and signaling to host-pathogen interactions. One of the most common ways of studying carbohydrates is through glycan release and subsequent analysis, usually through chromatography and mass spec. To this end, as part of our mission to empower innovation in glycoscience, we are proud to offer several glyco enzymes. Like all of our protein products, our enzymes are recombinant, ensuring minimum lot to lot variability. Additionally, each lot of enzyme is QC-tested against various substrates and certified free of protease and glycosidase contaminants.

Product Name Catalog Number Amount Glycoprotein? Optimal pH Activity
PNGase F GE01014,000 units; 20,000 units No 7.5-8.5 Cleaves N-linked glycans without core α1,3 fucose
PNGase F-II GE0201100 units No 6.5-7.5 Cleaves N-linked glycans with or without core fucose, both α1,6 and α1,3
α2,3 Sialidase GE0301 5,000 units; 50,000 units No 7.0-7.5 Cleaves terminal α2,3-linked sialic acid
O-GlcNAcase GE0401 1,000 units No 7.5 Cleaves O-linked β-N-Acetylglucosamine (GlcNAc)