Carbohydrates play a vast role in biology, from cell recognition and signaling to host-pathogen interactions. One of the most common ways of studying carbohydrates is through glycan release and subsequent analysis, usually through chromatography and mass spec. To this end, as part of our mission to empower innovation in glycoscience, we are proud to offer several glyco enzymes. Like all of our protein products, our enzymes are recombinant, ensuring minimum lot to lot variability. Additionally, each lot of enzyme is QC-tested against various substrates and certified free of protease and glycosidase contaminants.
|Product Name||Catalog Number||Amount||Glycoprotein?||Optimal pH||Activity|
|PNGase F||GE0101||4,000 units; 20,000 units||No||7.5-8.5||Cleaves N-linked glycans without core α1,3 fucose|
|PNGase F-II||GE0201||100 units||No||6.5-7.5||Cleaves N-linked glycans with or without core fucose, both α1,6 and α1,3|
|α2,3 Sialidase||GE0301||5,000 units; 50,000 units||No||7.0-7.5||Cleaves terminal α2,3-linked sialic acid|
|O-GlcNAcase||GE0401||1,000 units||No||7.5||Cleaves O-linked β-N-Acetylglucosamine (GlcNAc)|